Lampit (Nifurtimox Tablets): Uses, Contraindications, and Side Effects

What is LAMPIT and why it is used?

Lampit is nifurtimox-containing tablets. Nifurtimox is classified as an antiprotozoal drug used to treat Chagas disease which is caused by Trypanosoma cruzi.

Active Ingredient

Active ingredient of Lampit is Nifurtimox.

LAMPIT Contraindications

Patients who have a known hypersensitivity to nifurtimox or any of the excipients in LAMPIT, as well as patients who consume alcohol during therapy, should not use these tablets.

Is it safe in pregnancy?

When given to a pregnant woman, it can harm the fetus.

LAMPIT Side Effects

Here are some side effects associated with the use of these tablets:

  • Vomiting
  • Headache
  • Diarrhea
  • Loss of appetite
  • Rash
  • Dizziness
  • Urticarial
  • Anaemia
  • Nausea
  • Pyrexia
  • Eosinophilia
  • Abdominal pain

Genetotoxicity

Lampit is genotoxic in humans, in vitro in mammalian cell systems and a variety of bacterial species, and in vivo in rodents.

According to a study, the cytogenetic effect of nifurtimox in pediatric Chagas disease patients aged 7 months to 14 years revealed a 13-times increase in chromosomal abnormalities.

Manufacturer

It is manufactured by Bayer. It is available in two strengths

  • Nifurtimox 30 mg Tablets
  • Nifurtimox 120 mg Tablets

References

https://www.lampit.com/hcp
https://reference.medscape.com/drug/lampit-nifurtimox-342663
https://www.webmd.com/drugs/2/drug-179881/nifurtimox-oral/details

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